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Moxigen 400mg Tablet 1 Strip
Moxigen is indicated for the treatment of:
- Acute bacterial sinusitis
- Acute exacerbation of chronic bronchitis
- Community-acquired pneumonia
- Uncomplicated and complicated skin and skin structure infections
- Complicated intra-abdominal infections
- Pelvic inflammatory disease
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✅ Description:
Moxifloxacin is a 4th generation synthetic broad-spectrum fluoroquinolone antibacterial drug. It acts by inhibiting:
- Topoisomerase II (DNA gyrase)
- Topoisomerase IV, necessary for bacterial DNA replication, transcription, and repair.
Dosage & Administration
- Acute bacterial sinusitis: 400 mg once daily for 7-10 days.
- Acute exacerbation of chronic bronchitis: 400 mg once daily for 5-10 days.
- Community-acquired pneumonia: 400 mg once daily for 7-14 days.
- Uncomplicated skin and skin structure infections: 400 mg once daily for 7 days.
- Complicated skin and skin structure infections: 400 mg once daily for 7-21 days.
- Complicated intra-abdominal infections: 400 mg once daily for 5-14 days.
- Pelvic inflammatory disease: 400 mg once daily for 14 days.
Interaction
- Decreased absorption: When administered with antacids, sucralfate, multivitamins, and multivalent cations (e.g., iron or zinc).
- Enhanced risks: Concomitant use with NSAIDs may increase the risk of convulsions, and with warfarin may increase bleeding risk.
Contraindications
- Hypersensitivity to Moxifloxacin or other quinolones.
Side Effects
- Common: Nausea, vomiting, diarrhea, headache, dizziness.
Pregnancy & Lactation
- Pregnancy Category C: Not recommended during pregnancy and lactation.
Precautions & Warnings
- Increased risk of tendinitis and tendon rupture; discontinue if tendon pain or inflammation occurs.
- Avoid in patients with known prolongation of the QT interval, uncorrected hypokalemia, and those receiving Class IA or Class III antiarrhythmic agents.
Use in Special Populations
- Renal or hepatic impaired patients: No dose adjustment necessary.
- Pediatric patients: Safety and effectiveness not established in patients under 18 years.
Therapeutic Class
- 4-Quinolone preparations.
Storage Conditions
- Store in a dry place, protected from light and heat.
- Keep out of the reach of children.
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accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
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